The Rudnaya River Valley region has observed a high rate of cancer as well as chronic and acute illnesses due to the use of outdated mining technology and metal smelting. The district capital Dalnegorsk is contaminated with boron, sulfur, and heavy metals including lead, cadmium, and zinc. The second biggest town in the valley is Rudnaya Pristan, which translates into “mining port� and is built around the lead smelter and the seaport, is one of the most lead contaminated sites in Russia. The town has the highest rate of respiratory diseases in the region and other illnesses including neurological damage. Children there continued to have a higher blood lead levels even after the intervention began. For almost a century, lead and zinc ore produced in the local mines is processed at the refining factory in Dalnegorsk. The lead and zinc concentrate were transported in open cars to Rudnaya Pristan for smelting up until 2006. Lead and cadmium, the most potent toxins in the region, damage human health through inhalation of lead dust, playing with contaminated soil, eating produce grown on contaminated lands, and air pollution. These toxins inhibit the functioning and development of the nervous system and are particularly harmful to children, leading to permanent learning and behavior disorders. Common symptoms of lead poisoning include abdominal pain, headache, anemia, irritability, and in severe cases seizures, coma, and death.

Copsa Mica was one of Europe’s most polluted towns in the 1990s and remains the most polluted town in Romania to this day. Two factories Carbosin that produced carbon black and Sometra, a non-ferrous metallurgical smelter were behind this pollution. Carbosin shut down in 1993 but the smelter is still operational.

Since 1922, adults and children in La Oroya, Peru - a mining town in the Peruvian Andes and the site of a poly-metallic smelter - have been exposed to the toxic emissions and wastes from the plant. Peru's Clean Air Act cites La Oroya in a list of Peruvian towns suffering from critical levels of air pollution, but action to clean up and curtail this pollution. Currently owned by the Missouri-based Doe Run Corporation, the plant has been largely responsible for the dangerously high lead levels found in children's blood. Activities are now underway to curtail emissions and clean up legacy residual contamination. Ninety-nine percent of children living in and around La Oroya have blood lead levels that exceed acceptable limits, according to studies carried out by the Director General of Environmental Health in Peru in 1999. Lead poisoning is known to be particularly harmful to the mental development of children. A survey conducted by the Peruvian Ministry of Health in 1999 revealed blood lead levels among local children to be dangerously high, averaging 33.6 �g/dL for children between the ages of 6 months to ten years, triple the WHO limit of 10 �g/dL. Neurologists at local hospitals state that even newborn children have high blood lead levels, inherited while still in the womb. Sulfur dioxide concentrations also exceed the World Health Organization guidelines. Soil contamination is now being studied and a plan for clean up is in progress. Numerous studies have been carried out to assess the levels and sources of lead and other metals still being deposited in La Oroya. Limited testing has revealed lead, arsenic and cadmium soil contamination throughout the town. A detailed public health program has been implemented at the neighborhood level, focusing on children's health including bi-annual blood testing of all children. This has been operational for several years.

The Coca-Cola bottling plant at Plachimada is located along the Palakkad-Meenakshipuram-Pollchi road, around three kilometers to the north of the Meenkara dam reservoir and a few hundred meters west of the Kambalathara and Vengalakkayam storage reservoirs.

The bottling plant started production in 1998 on a 42- acre plot in violation of the Kerala Land Utilisation Act, 1967, intended to prevent the use of agricultural land for non-agricultural purposes. Hindustan Coca-Cola Beverages Limited (HCBL) has faced a host of complaints and agitation from local people over water and soil pollution. The issue has been raised in the media with a focus on depletion of water and its contamination. Test results of the well water and the sludge have proved the presence of contamination.